Human papillomavirus (HPV) is a major cause of cervical cancer in women and reason of oropharyngeal and anogenital cancer, and genital warts in men and women.
HPV infects basal epithelial cells and mucosal cells in the anus, vagina, vulva, penis, and oropharynx.
There are more than 200 HPV genotypes known. HPV genotypes are classified under highrisk (HR), medium-risk (MR), or low-risk (LR) groups according to their known risk of developing cancer.
HPV infections with high-risk genotypes (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68), can cause cancer development.
Detection with the kit is achieved via rapid nucleic acid extraction from cervical, vaginal and penile swab samples followed by multiplex qPCR targeting the genomic DNA regions specific to the target agents inreal-time PCR instruments that are equipped with FAM, HEX, ROX, and CY5 detection channels.
The kit components are shown in the table below.
| Reagents | 100 reactions |
| Reaction mix | 4x1000 µl |
| HHPVOligo Mix 1 | 500 µl |
| HHPVOligo Mix 2 | 500 µl |
| HHPVOligo Mix 3 | 500 µl |
| HHPVOligo Mix 4 | 500 µl |
| PC-HHPV 1 | 100 µl |
| PC-HHPV 2 | 100 µl |
| PC-HHPV 3 | 100 µl |
| PC-HHPV 4 | 100 µl |
| NTC | 1000 µl |
